abstract：:The goal of this study was to explore the impact of 2-deoxglucose or malonate individually or in combination on the level of cell energy (adenosine-5'-triphosphate) and oxidative stress in 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary proliferation in rats. A total of 60 adult female Sprague Dawley rats were r...

journal_title：Toxicology and industrial health

authors： Moselhy SS,Kumosani TA,Al-Malki AL,Naif AA

更新日期：2015-04-01 00:00:00

abstract：:Diazinon (DZN) is one of the most widely used insecticides in agricultural pest control. Previous studies have shown that DZN may induce hepatotoxicity. Reactive oxygen species and apoptosis pathways are involved in the toxicity of DZN. Crocin, a constituent of saffron, has hepatoprotective effects due to its antioxid...

journal_title：Toxicology and industrial health

authors： Lari P,Abnous K,Imenshahidi M,Rashedinia M,Razavi M,Hosseinzadeh H

更新日期：2015-04-01 00:00:00

abstract：:Endothelial adhesion plays an important role in the process of atherosclerosis, which is regulated by endothelial adhesion molecules and chemoattractant molecules. In some areas of China, citreoviridin (CIT) is considered a risk factor for the development of atherosclerosis. Here, we investigated the role of CIT in ad...

journal_title：Toxicology and industrial health

authors： Hou H,Zhou R,Jia Q,Li Q,Kang L,Jiao P,Li D,Jiang B

更新日期：2015-03-01 00:00:00

abstract：:The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

journal_title：Toxicology and industrial health

authors： Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

更新日期：2015-03-01 00:00:00

abstract：:The aim of the present study was to assess the influence of curcumin on liver regeneration after partial hepatectomy (PH) in rats. A total of 24 male Sprague Dawley rats were divided into three groups: sham-operated (SH), PH, and PH + curcumin; each group contains eight animals. The rats in curcumin-treated groups wer...

journal_title：Toxicology and industrial health

authors： Toydemir T,Kanter M,Erboga M,Oguz S,Erenoglu C

更新日期：2015-02-01 00:00:00

abstract：:The effects of trona (Kaun), a food additive, on the redox status of the liver and kidney of male Wistar rats were investigated. A total of 60 male rats (145 ± 2.52 g) were grouped into four: A, B, C and D, where group A (the control) received 1 mL of distilled water orally while those in groups B, C and D (test group...

journal_title：Toxicology and industrial health

authors： Ajiboye TO,Komolafe YO,Yakubu MT,Ogunbode SM

更新日期：2015-02-01 00:00:00

abstract：:Holothuria polii (Delle Chiaje, 1823) (Holothuriidae) is a sea cucumber inhabiting Mediterranean Sea coast of Egypt. The bioactive compound of its tegument has antifungal, antibacterial and antiparasitic effects. The present study aims to elucidate the structure of the bioactive material of H. polii for pharmacologica...

journal_title：Toxicology and industrial health

authors： Omran NE,Khedr AM

更新日期：2015-01-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AHR) is one of the principal xenobiotic, nuclear receptor that is responsible for the early events involved in the transcription of a complex set of genes comprising the CYP450 gene family. In the present computational study, homology modelling and molecular docking were carried out with...

journal_title：Toxicology and industrial health

authors： Panda R,Cleave AS,Suresh PK

更新日期：2014-09-01 00:00:00

abstract：:Paraphenylene diamine (PPD) hair dye poisoning is a common health problem in the Middle East and Indian subcontinent. It is the most common cause of suicide intent especially among females. We hereby present a 27-year-old female who presented with a clinical feature of PPD poisoning due to a suicidal attempt, and she ...

journal_title：Toxicology and industrial health

authors： Abdelraheem MB,Elbushra M,Ali el-T,Ellidir RA,Bushara AI,Abdelraheem WB,Zijlstra EE

更新日期：2014-09-01 00:00:00

abstract：:In the present study, we attempted to elucidate the induction of autophagy in rat hepatocytes by a low concentration of mercury. Hepatocytes treated with different doses of mercuric chloride (HgCl2; 1, 2.5, 5 and 10 µM) and at different time intervals (0 min, 30 min, 1 h, 2 h and 4 h) show autophagic cell death only a...

journal_title：Toxicology and industrial health

authors： Chatterjee S,Ray A,Mukherjee S,Agarwal S,Kundu R,Bhattacharya S

更新日期：2014-08-01 00:00:00

abstract：:Cyclophosphamide (CP) is an alkylating agent that has been considered effective for cancer treatment. Lycopene, the pigment in tomato fruits, has beneficial effect in the treatment of some diseases. The goal of this study is to evaluate the protective effect of lycopene alone or combined with melatonin (Mel) in inhibi...

journal_title：Toxicology and industrial health

authors： Al-Malki AL

更新日期：2014-07-01 00:00:00

abstract：:Organophosphate poisoning is a life-threatening condition, which is being responsible for the symptoms due to cholinergic effects. Clinical status and blood levels of cholinesterase are used its diagnosis. While atropine and pralidoxime (PAM) appear as essential medications, hemofiltration treatments and lipid solutio...

journal_title：Toxicology and industrial health

authors： Karakus A,Celik MM,Karcioglu M,Tuzcu K,Erden ES,Zeren C

更新日期：2014-06-01 00:00:00

abstract：:Trivalent chromium (Cr) is an environmental contaminant, which is extensively used in tanning industries throughout the world and causes various forms of health hazards in tannery workers. Therefore, a cross-sectional study design was used to evaluate the DNA damage and oxidative stress condition in tannery workers ex...

journal_title：Toxicology and industrial health

authors： Ambreen K,Khan FH,Bhadauria S,Kumar S

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:Various authors who studied the effects of aluminium (Al) exposure on the neurocognitive system in the last 30 years have reached different and often contradictory conclusions. The aim of this study is to help clarify the effects that the metal causes on cognitive ability in a group of naval welders exposed ...

journal_title：Toxicology and industrial health

authors： Giorgianni CM,D'Arrigo G,Brecciaroli R,Abbate A,Spatari G,Tringali MA,Gangemi S,De Luca A

更新日期：2014-05-01 00:00:00

abstract：:Carbendazim is a broad spectrum carbamate fungicide used in the control of various fungal pathogens. Licorice (Glycyrrhiza glabra) is one of the widely used medicinal plants in oriental nations. The present work studied the effect of licorice aqueous extract on carbendazim-induced testicular toxicity in albino rats. A...

journal_title：Toxicology and industrial health

authors： Sakr SA,Shalaby SY

更新日期：2014-04-01 00:00:00

abstract：:This experiment is designed to investigate the positive effects of commercial nanosilver compound on blood parameters in experimental aflatoxicosis in broiler chickens. For this, 270 one-day-old broiler chickens were randomly divided into six treatment groups with three replicates. The experimental groups were group A...

journal_title：Toxicology and industrial health

authors： Gholami-Ahangaran M,Zia-Jahromi N

更新日期：2014-03-01 00:00:00

abstract：:Many episodes of low back pain are disabling, thus making it one of the costly occupational health problem. The proper alignment and lifting operations during drilling process frequently exposed the oil-drilling workers to unusual strain on the spine and thus make them susceptible for developing low back pain. The pre...

journal_title：Toxicology and industrial health

authors： Tiwari RR,Saha A

更新日期：2014-02-01 00:00:00

abstract：:Microbiological studies were carried out on microbial contamination and antimicrobial activity of sea cucumber Holothuria polii collected from Mediterranean Sea at Abu-kir shore of Alexandria, Egypt. The obtained results revealed the presence of isolates of five human Gram-negative pathogenic bacteria, representing fi...

journal_title：Toxicology and industrial health

authors： Omran NE,Allam NG

更新日期：2013-11-01 00:00:00

abstract：:Molecular mechanisms in the pathogenesis of silicosis are not fully understood. Exposure to crystalline silica leads to the activation of signaling pathways controlling the production and secretion of inflammatory mediators. Inflammatory cytokines are noted as important candidate genes for fibrotic lung diseases. Cyto...

journal_title：Toxicology and industrial health

authors： Mohebbi I,Rad IA,Bagheri M

更新日期：2013-10-01 00:00:00

abstract：:Oxidative stress is accepted as a potential responsible mechanism in the pathogenesis of radiocontrast media (RCM)-induced hepatotoxicity. Therefore, we aimed to investigate the protective effects of ebselen against RCM-induced hepatotoxicity by measuring tissue oxidant/antioxidant parameters and histological changes ...

journal_title：Toxicology and industrial health

authors： Basarslan F,Yilmaz N,Davarci I,Akin M,Ozgur M,Yilmaz C,Ulutas KT

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study is to evaluate the role of curcumin on acute lung injury induced by intestinal ischaemia/reperfusion (I/R). A total of 30 male Wistar albino rats were divided into 3 groups: sham, I/R, and I/R + curcumin; each group contains 10 animals. Sham group animals underwent laparotomy without I/R injury. ...

journal_title：Toxicology and industrial health

authors： Guzel A,Kanter M,Guzel A,Yucel AF,Erboga M

更新日期：2013-08-01 00:00:00

abstract：:Pyrrolizidine alkaloid isoline is isolated from the traditional Chinese medicine Ligularia duciformis. Our previous reports have already demonstrated isoline-induced liver injury in mice. The present study is designed to observe the involvement of intracellular reduced glutathione (GSH) in isoline-induced cytotoxicity...

journal_title：Toxicology and industrial health

authors： Chen Y,Ji L,Xiong A,Yang L,Wang Z

更新日期：2013-07-01 00:00:00

abstract：:The mechanism by which granulocyte colony-stimulating factor (G-CSF) could lead to the protection from liver injury is not well known. Therefore, the resolution of this role needs further basic and clinical experimental investigation. Acute liver injury was induced in rats by single intraperitoneal injection of a 0.50...

journal_title：Toxicology and industrial health

authors： Qujeq D,Abassi R,Faeizi F,Parsian H,Faraji AS,Taheri H,Tatar M,Elmi MM,Halalkhor S

更新日期：2013-07-01 00:00:00

abstract：:In the present study, the single and combined neurotoxic effects of benzo[a]pyrene ([BaP] 0.0, 0.5, and 5.0 mg/kg body weight; intragastric administration) and lead acetate (0.0, 5.4, and 54.0 mg/L; by drinking water) were examined on KunMing mice. In the Morris water maze, results showed that BaP and lead induced syn...

journal_title：Toxicology and industrial health

authors： Youbin Q,Chengzhi C,Yan T,Xuejun J,Chongying Q,Bin P,Baijie T

更新日期：2013-06-01 00:00:00

abstract：:Excessive exposure to nickel may cause health effects on the blood, lung, nose, kidney, reproductive system, skin and the unborn child. In the present study, we found that Ni²⁺ exposure led to a time- and dose-dependent proliferation arrest and death in human leukemia HL-60 cells. In the presence of 1 mM Ni²⁺, reactiv...

journal_title：Toxicology and industrial health

authors： Chen J,Han J,Wang J

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the chemopreventive potential of organoselenium compounds (Se I and Se II) in the well-established rat model treated with 7,12-dimethylbenz[a]anthracene (DMBA), by monitoring the extent of tyrosine hydroxylase (TH) activity, adrenomedullin (ADM) level and total RNA level ...

journal_title：Toxicology and industrial health

authors： Talas ZS,Ozdemir I,Ates B,Gok Y,Yilmaz I

更新日期：2013-04-01 00:00:00

abstract：:Methiocarb (MC) is a widely used carbamate pesticide in agriculture and health programs. Although the main molecular mechanism of carbamate toxicity involves acetylcholinesterase inhibition, studies have also implicated the induction of oxidative stress. Therefore, the present study was aimed to evaluate the effect of...

journal_title：Toxicology and industrial health

authors： Ozden S,Catalgol B,Gezginci-Oktayoglu S,Karatug A,Bolkent S,Alpertunga B

更新日期：2013-02-01 00:00:00

abstract：:Occupational exposure in a copper smelting industry may produce various adverse health effects including cancer. Despite a number of well-documented studies reporting an increased risk of cancer among copper smelter workers, the data on genotoxic effects in this industry are scarce. In view of the above, an assessment...

journal_title：Toxicology and industrial health

authors： De Olivera JV,Boufleur LA,Dos Santos CE,Dias JF,Squeff CH,Silva GR,Ianistcki M,Benvegnú VC,Da Silva J

更新日期：2012-10-01 00:00:00

abstract：:The aim of this study was to evaluate the antiapoptotic and proliferative activity of curcumin (Cur) on the ovarian follicles in mice exposed to whole body ionizing radiation (Rd). The mice were exposed to 8.3 gray whole body Rd, and Cur groups were given as a daily dose of 100 mg/kg of Cur for 10 days (10 days before...

journal_title：Toxicology and industrial health

authors： Aktas C,Kanter M,Kocak Z

更新日期：2012-10-01 00:00:00

abstract：:An analytical method using natural analcime zeolite modified with tppz (2,3,5,6-tetra-pyridylpyrazine) for preconcentration of cadmium, in a column system, and their sequential determination by flame atomic absorption spectrometry (FAAS), was developed. In this work, cadmium was adsorbed onto natural analcime zeolite ...

journal_title：Toxicology and industrial health

authors： Saljooghi AS,Saljoghi ZS

更新日期：2012-10-01 00:00:00

abstract：:The aim of the present study was to provide baseline data on the prevalence of histopathological liver lesions in Acanthopagrus latus under experimental mercury exposure. Experimental study was at seawater recirculatory tanks. Mercury concentrations were determined using a standard cold vapour atomic absorption. Histo...

journal_title：Toxicology and industrial health

authors： Safahieh A,Hedayati A,Savari A,Movahedinia A

更新日期：2012-08-01 00:00:00

abstract：:Enzymes with hydroxylating activity on alkanes have potential application as biotransformation catalysts in chemical and pharmaceutical industry. Genome of Alcanivorax borkumensis, a marine bacterium with hydrocarbon dissimilation activity, contains at least two P450 monooxygenases and two nonheme monooxygenases, AlkB...

journal_title：Toxicology and industrial health

authors： Eidani SZ,Shahraki MK,Gasemisakha F,Hahsemi M,Bambai B

更新日期：2012-07-01 00:00:00

abstract：:The morphological changes of ricin-induced apoptosis in a human cervical cancer cell line were studied. To shed light on the mechanism of action of ricin toxin (RT) at the cellular level, we examined cell growth, apoptosis, changes of mitochondrial membrane potential (MMP) and cytochrome C translocation in HeLa cells ...

journal_title：Toxicology and industrial health

authors： Liao P,Liu W,Li H,Gao H,Wang H,Li N,Xu N,Li J,Wan J,Liu L,Sun Y

更新日期：2012-06-01 00:00:00

abstract：:The present study was designed to evaluate the effect of Plantago major Linnaeus (PM) extract on serum total sialic acid (TSA), lipid-bound sialic acid (LSA), some trace elements (copper (Cu), zinc (Zn) and iron) and mineral levels (magnesium, calcium and sodium) in Wistar albino rat administrated 7,12-dimethylbenz(a)...

journal_title：Toxicology and industrial health

authors： Oto G,Ekin S,Ozdemir H,Levent A,Berber I

更新日期：2012-05-01 00:00:00

abstract：:The gem-polishing industry in Jaipur, India employs a substantial proportion of children. The process of polishing may result in exposure to chromium in working children. Thus, this study aims to find out the levels of chromium in these working children and the associated factors. Blood samples were analysed for chrom...

journal_title：Toxicology and industrial health

authors： Tiwari RR,Saha A,Sathwara NG,Parikh JR

更新日期：2012-03-01 00:00:00

abstract：:Mercury has been used in many domains of human activities for many years, although in any form mercury is reported to be toxic. On the other hand, lichens have been used in the treatment of several diseases such as tuberculosis, hemorrhoids, ulcer, dysentery and cancer. Animal investigations on some common lichen spec...

journal_title：Toxicology and industrial health

authors： Turkez H,Dirican E

更新日期：2012-02-01 00:00:00

abstract：:An investigation was conducted to evaluate the ability of two chelators, deferasirox and desferrioxamine (DFO), in removing cadmium from biological system. The potential efficiency of those chelators were investigated after cadmium administration for 60 days following two dose levels of 20 and 40 mg/kg body weight dai...

journal_title：Toxicology and industrial health

authors： Fatemi SJ,Saljooghi AS,Balooch FD,Iranmanesh M,Golbafan MR

更新日期：2012-02-01 00:00:00

abstract：:Electrical and electronic waste (E-waste) has now become the fastest growing solid waste around the world. Primitive recycling operations for E-waste have resulted in severe contamination of toxic metals and organic chemicals in the related areas. In this study, six dust and soil samples collected from E-waste recycli...

journal_title：Toxicology and industrial health

authors： Wang L,Hou M,An J,Zhong Y,Wang X,Wang Y,Wu M,Bi X,Sheng G,Fu J

更新日期：2011-10-01 00:00:00

abstract：:Yoghurt is a popular dairy product in Iran because of its beneficial influence on human health and nutritional value. Aflatoxin M1 (AFM1) is the metabolite of potential carcinogen aflatoxin B1, which can contaminate milk through the feed and is not eliminated by common processing heat treatment. An analytical method u...

journal_title：Toxicology and industrial health

authors： Tabari M,Karim G,Ghavami M,Chamani M

更新日期：2011-08-01 00:00:00

abstract：:The aim of the study is to assess whether occupational exposure to urban stressors could cause alterations in urinary metanephrines levels in traffic policemen vs administrative staff of municipal police. A total of 258 subjects were included in the study: 129 traffic policemen exposed to urban stressors (68 males and...

journal_title：Toxicology and industrial health

authors： Sancini A,Tomei G,Ciarrocca M,Pimpinella B,Samperi I,Fiaschetti M,Scimitto L,Tasciotti Z,Caciari T,Tomei F

更新日期：2011-05-01 00:00:00